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At One Ventures

San Francisco, CAAT-ONE-VENTURES
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Dossier Summary

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Classification
Slugat-one-ventures
HQSan Francisco, CA
Stage FocusAs of November 2025, At One has invested in 43 companies,…
Intel StatusAccepting submissions
🔥 BERNIE'S HOT TAKE

Here's what founders actually say about working with At One: while they spend most of their time with other investors explaining the science behind their company, the At One team truly understands the technical fundamentals and quickly moves to helpful conversations about go-to-market and business issues. They're known for serious portfolio support with dedicated resources for talent, marketing, patent strategy, and manufacturing—particularly focused on helping companies scale manufacturing and achieve superior unit economics. Their secret weapon is four engineering EIRs with manufacturing backgrounds who help overcome common scale-up obstacles like building first-of-a-kind facilities and reducing CapEx/OpEx. The flip side? This is serious deep tech with long timelines—don't expect quick exits or SaaS-like growth curves.

KEY TAKEAWAYS
  • Best for: Deep tech climate founders who need investors who actually understand the physics
  • Known for: Exceptional technical due diligence and hands-on manufacturing scale-up support
  • Watch out for: Long development cycles and capital-intensive paths to commercialization
Investment Thesis

At One Ventures uses a formalized "Triad" investment thesis that only backs companies simultaneously deploying disruptive deep tech, fundamentally upending incumbent unit economics, and driving strong climate and nature-positive outcomes. Their goal is to catalyze a world where humanity becomes a net positive to nature.

Stage & Sector Focus

As of November 2025, At One has invested in 43 companies, primarily in Seed rounds in US-based startups. Their investments span high tech, food and agriculture tech, and environment tech. They lead 90% of their first placements and have 35 companies in portfolio with 11 already booking sales.

Notable Portfolio
Ascend ElementsColossal BiosciencesMonarch TractorDalan Animal HealthModern HydrogenCruz FoamFinless FoodsMightyFly
Key Partners
Tom Chi
Managing Partner & Founder

Former Google X founding team member who helped build Google Glass and early self-driving cars. With a background in physics, electrical engineering, and robotics, Tom scaled Google X from 6 people to 600. Left Google after watching a coral reef near his Hawaii home die, realizing the urgency of climate change.

Laurie Menoud
Founding Partner

Over a decade of deep tech commercialization experience, played roles in chemical industry (Solvay, BASF) and built a dozen ventures out of DoD research programs at SRI International. Biotechnologist by training and ecological transition advocate. Serves on Ascend Elements' board and has played an instrumental role in their growth.

Helen Lin
Partner

Over 2 decades of corporate finance experience across four continents, with background in M&A (Baird, Houlihan Lokey), multinational banking operations, and designing financial products for base of pyramid customers at FINCA Impact Finance in Africa. Loves solving big problems creatively.

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